Last Updated on 2025 年 12 月 9 日 by 総合編集組
What is Creon? A Kid-Friendly Guide to Pancreatic Enzyme Replacement Therapy (PERT)
Creon is a special medicine that helps people whose pancreas is “tired” and can’t make enough digestive enzymes. Think of it as three tiny chefs in a capsule who help break down fats, proteins, and carbs so your body can use the food properly.
How Does Creon Work Inside the Body? (Super Easy Explanation) When you swallow a Creon capsule, it travels to your stomach. The hard shell opens quickly, but the hundreds of tiny beads inside have a magic coat that protects them from stomach acid. These beads mix perfectly with your food and wait patiently. Only when they reach the small intestine (where the environment becomes less acidic, pH > 5.5) do the beads dissolve and release three powerful enzymes: lipase (cuts fat), protease (cuts protein), and amylase (cuts starch). This timing is perfect – exactly when and where your body needs them most!
Special Pharmacokinetics: Creon Never Enters Your Blood Unlike most medicines that go into your blood, Creon works only inside the gut and is never absorbed into the bloodstream. After doing their job, the enzymes are broken down and leave the body with poop. This makes Creon very safe, even for pregnant women and small children.
Who Needs Creon? Main Medical Conditions (On-Label Uses)
- Cystic Fibrosis (CF): The most common reason in children
- Chronic Pancreatitis: Long-term pancreas inflammation
- After pancreas surgery (pancreatectomy)
- Pancreatic duct blockage or cancer-related issues Without treatment, patients suffer from oily, floating, smelly stools (steatorrhea), weight loss, and malnutrition.
Real User Reviews from Around the World (2025 Update) On Drugs.com, Creon scores 6.4/10 from over 64 reviews. Most users say: ✓ “Finally no more oily stools!” ✓ “I gained weight and energy back” ✓ “Life-changing for my child with CF” Some mention temporary bloating or stomach pain in the first 1–2 weeks, but symptoms usually disappear after dose adjustment. Parents love that beads can be sprinkled on applesauce for kids who can’t swallow capsules.
2025 Taiwan Shortage Situation In late 2025, Taiwan experienced a temporary shortage of Creon due to global supply chain issues. The government has activated emergency imports, and doctors are helping patients with alternative plans. Never stop taking it suddenly – always talk to your doctor.
How to Take Creon Correctly
- Take with every meal and snack containing fat
- Swallow whole or sprinkle beads on acidic food (applesauce, yogurt)
- Never crush or chew – it destroys the protective coating
- Dosage is individualized based on fat content of meals and body weight
Safety & Side Effects Very rare serious side effects. Most common mild issues: bloating, gas, constipation, or diarrhea during the first weeks. Allergic reactions to pork proteins are extremely rare but possible.
Why Creon is Considered the Gold Standard Thanks to its patented Minimicrospheres® technology, Creon releases enzymes at exactly the right time and place – better than most generic pancreatic enzymes. Clinical studies (over 30 trials) prove it significantly improves fat absorption and quality of life.
Final Thoughts Creon isn’t just a pill – it’s a lifeline for thousands of children and adults with exocrine pancreatic insufficiency. With proper medical guidance, it allows patients to eat normally, grow well, and enjoy life without constant digestive distress.
